PARIS - The number of specialized cells in the storage of lipids, or adipocytes, defined in childhood, stays constant throughout life, according to a study appeared in the British scientific journal "Nature". They are renewed by almost 10% per year.
A team of researchers directed by Kirsty Spalding of the Karolinska Institute in Stockholm, found that the two main determinants of obesity are the number of adipocytes and their size.
However, by investigating cells originating from liposuction or abdominal reconstruction, the researchers were able to establish that after childhood, the number of adipocytes stays constant in adults, with a steady renewal of about 10% annually.
Cell Substitution
"The total number of fat cells in the body is constant since the production of new cells is offset by an equal loss of cells that die," said Peter Arner, the co-author of the research.
Therefore, a reduction of weight in adulthood only diminishes the mass of cells, which is quickly recovered by new ones.
"The new fat cells that lay down fat which is produced during and after weight reduction need to quickly grow in lipids," notes Peter Arner. "This would explain, at least partially, why it's so hard to maintain the weight one has reached after a reducing diet."
Age and Treatment of Overweight
The researchers also found that adipocytes begin to develop earlier in the obese (around the age of 2 years) than in people with normal weight (between 5 and 6 years), moreover, the growth in weight is two times faster for the obese but it also stops earlier (16 years against 18 years in others).
This study confirms the statistics showing that the majority of adults are obese since childhood, only 10% of children with normal weight become obese when growing up and more than three-quarters of obese children have been keeping this over-weight.
These data, on the number of adipocytes determined in childhood and the regular-renewal of these cells should, according to researchers, make it possible to define new targets for obesity therapy , in childhood by acting to limit the number of adipocytes, or in adulthood, by reducing the substitution of dead cells with new ones.
Women, Age and Overweight
Women in their Thirties
The waist is tending to grow rapidly, especially, for females between 30 and 40 years. This could indicate that obesity in middle-aged and mature women is more prevalent than previously assumed, wrote the authors of a study published in the specialist journal “BMC Public Health”.
It is possible that experiencing several pregnancies results in obesity, according to Dr. Marques-Vidal. But this is a hypothesis that has to be scientifically examined. There is, therefore, no recommendation for specific groups within the population. “Preventive measures should apply to the entire population” says the doctor.
Herbal Medicine against Obesity
Herbal medicine remains certainly the best way to manage a slimming weight diet. Over-weight has two main sources, the first is an uncontrolled appetite and the second is low metabolic rates related to a food absorption dysfunction. The function of herbal drugs would be to suppress the voracious appetite or to boost the metabolism in order to increase metabolic rates in the safest way ever. Self-conviction is also very important to control the huge appetite, if you are not mentally ready to begin a diet, the whole operation is utterly useless. You may be more helpless towards fatness caused by low metabolic rates because you may not be a big eater but involuntary fat.
Herbal ingredients will enhance your food absorption through increasing your metabolic rates with no one side-effects. Therefore, herbal weight loss seems to be the safer way to undergo a slimming weight program.
Ines Khalsi is a sports professor, she has acquired a considerable background in weight loss treatments; she went across numerous medicines and discovered that herbal medicine is the safer way to lose superfluous kilos. She also found out that herbal medicine can be used to heal many physical deficiencies. If you are interested in herbal products please visit:
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